catalog number :
MBS820653
products full name :
Anti-CD131 Antibody
products short name :
[CD131]
products name syn :
[IL3RB; IL5RB; Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131]
other names :
[cytokine receptor common subunit beta; Cytokine receptor common subunit beta; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131]
products gene name :
[CSF2RB]
other gene names :
[CSF2RB; CSF2RB; CD131; IL3RB; IL5RB; SMDP5; CDw131; IL3RB; IL5RB]
uniprot entry name :
IL3RB_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
Recognizes endogenous levels of CD131 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipping: Blue ice. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD131. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to CD131
ncbi acc num :
NP_000386.1
ncbi gb acc num :
NM_000395.2
ncbi pathways :
Apoptosis Pathway (83060); Apoptosis Pathway (470); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL-3 Signaling Pathway (198881); IL-5 Signaling Pathway (198770); Immune System Pathway (106386); Interleukin Receptor SHC Signaling Pathway (187095); Interleukin-2 Signaling Pathway (205110)
ncbi summary :
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
uniprot summary :
CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; interleukin-5 receptor activity; interleukin-3 receptor activity; receptor activity. Biological Process: response to lipopolysaccharide; respiratory gaseous exchange; signal transduction. Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5