catalog number :
MBS820633
products full name :
Anti-RNASE3 Antibody
products short name :
[RNASE3]
products name syn :
[ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3]
other names :
[eosinophil cationic protein; Eosinophil cationic protein; eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease; ribonuclease, RNase A family, 3; Ribonuclease 3; RNase 3]
products gene name :
[RNASE3]
other gene names :
[RNASE3; RNASE3; ECP; RNS3; ECP; RNS3; ECP; RNase 3]
uniprot entry name :
ECP_HUMAN
specificity :
Recognizes endogenous levels of RNASE3 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RNASE3. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to RNASE3
ncbi acc num :
NP_002926.2
ncbi gb acc num :
NM_002935.2
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532)
ncbi summary :
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]
uniprot summary :
RNASE3: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. Belongs to the pancreatic ribonuclease family. Protein type: EC 3.1.27.-; Secreted, signal peptide; Ribonuclease; Secreted. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular space; extracellular region. Molecular Function: nucleic acid binding; endonuclease activity; ribonuclease activity. Biological Process: defense response to Gram-positive bacterium; innate immune response in mucosa; RNA catabolic process; antibacterial humoral response