product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-PI3K C2 gamma Antibody
catalog :
MBS820611
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
MyBioSource MBS820611 image 1
Western blot analysis of PI3K C2 gamma expression in CEM (A), HeLa (B), NIH3T3 (C), PC12 (D) whole cell lysates.
product information
catalog number :
MBS820611
products type :
Antibody
products full name :
Anti-PI3K C2 gamma Antibody
products short name :
[PI3K C2 gamma]
products name syn :
[Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma]
other names :
[phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform 1; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma; Phosphoinositide 3-kinase-C2-gamma]
products gene name :
[PIK3C2G]
other gene names :
[PIK3C2G; PIK3C2G; PI3K-C2GAMMA; PI3K-C2-gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma]
uniprot entry name :
P3C2G_HUMAN
clonality :
Polyclonal
host :
unknown
reactivity :
Human, Mouse, Rat, Monkey
sequence length :
1486
specificity :
Recognizes endogenous levels of PI3K C2 gamma protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Source: Rabbit. Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PI3K C2 gamma. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to PI3K C2 gamma
ncbi gi num :
571026668
ncbi acc num :
NP_001275701.1
ncbi gb acc num :
NM_001288772.1
uniprot acc num :
O75747
ncbi pathways :
3-phosphoinositide Biosynthesis Pathway (545314); 3-phosphoinositide Biosynthesis Pathway (138600); Inositol Phosphate Metabolism Pathway (82987); Inositol Phosphate Metabolism Pathway (362); Insulin Signaling Pathway (198845); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PI Metabolism Pathway (645332); Phosphatidylinositol Signaling System Pathway (83052)
ncbi summary :
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
uniprot summary :
PIK3C2G: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis. Belongs to the PI3/PI4-kinase family. Protein type: EC 2.7.1.154; Carbohydrate Metabolism - inositol phosphate; Motility/polarity/chemotaxis; Kinase, lipid. Chromosomal Location of Human Ortholog: 12p12. Cellular Component: plasma membrane; phosphoinositide 3-kinase complex; cytosol. Molecular Function: phosphatidylinositol phosphate kinase activity; 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4-phosphate 3-kinase activity; phosphoinositide binding; ATP binding. Biological Process: phosphoinositide-mediated signaling; phosphoinositide phosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process; chemotaxis
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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