catalog number :
MBS820539
products full name :
Anti-ANT2 Antibody
products short name :
[ANT2]
products name syn :
[ANT2; ADP/ATP translocase 2; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; Adenine nucleotide translocator 2; ANT 2; Solute carrier family 25 member 5]
other names :
[ADP/ATP translocase 2; ADP/ATP translocase 2; ADP/ATP translocase 2; ANT 2; ADP/ATP carrier protein; ADP,ATP carrier protein 2; solute carrier family 25 member 5; ADP,ATP carrier protein, fibroblast isoform; adenine nucleotide translocator 2 (fibroblast); solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; Adenine nucleotide translocator 2; ANT 2; Solute carrier family 25 member 5Cleaved into the following chain:ADP/ATP translocase 2, N-terminally processed]
products gene name :
[SLC25A5]
other gene names :
[SLC25A5; SLC25A5; T2; T3; 2F1; AAC2; ANT2; ANT2; ANT 2]
uniprot entry name :
ADT2_HUMAN
reactivity :
Human, Rat, Bovine, Monkey, Sheep
specificity :
Recognizes endogenous levels of ANT2 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ANT2. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to ANT2
ncbi acc num :
NP_001143.2
ncbi gb acc num :
NM_001152.4
ncbi mol weight :
32,852 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Disease Pathway (530764); Electron Transport Chain Pathway (198860); HIV Infection Pathway (105983); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Host Interactions Of HIV Factors Pathway (106010); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512)
ncbi summary :
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
uniprot summary :
SLC25A5: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the mitochondrial carrier family. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Mitochondrial; Transporter. Chromosomal Location of Human Ortholog: Xq24. Cellular Component: mitochondrion; membrane; integral to plasma membrane; mitochondrial inner membrane; nucleus. Molecular Function: protein binding; adenine transmembrane transporter activity. Biological Process: adenine transport; viral reproduction; transport; positive regulation of cell proliferation; energy reserve metabolic process; transmembrane transport; regulation of insulin secretion; chromosome segregation