catalog number :
MBS820445
products full name :
Anti-GNG12 Antibody
products short name :
[GNG12]
products name syn :
[Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12]
other names :
[guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; G-protein gamma-12 subunit; guanine nucleotide binding protein (G protein), gamma 12]
products gene name :
[GNG12]
other gene names :
[GNG12; GNG12]
uniprot entry name :
GBG12_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Monkey, Rabbit
specificity :
Recognizes endogenous levels of GNG12 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GNG12. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to GNG12
ncbi acc num :
NP_061329.3
ncbi gb acc num :
NM_018841.5
ncbi pathways :
ADP Signalling Through P2Y Purinoceptor 1 Pathway (161061); ADP Signalling Through P2Y Purinoceptor 12 Pathway (161060); Activation Of G Protein Gated Potassium Channels Pathway (366226); Activation Of GABAB Receptors Pathway (187181); Activation Of Kainate Receptors Upon Glutamate Binding Pathway (161043); Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway (105923); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Aquaporin-mediated Transport Pathway (187187); Ca2+ Pathway (941399)
uniprot summary :
G-gamma 12: a guanine nucleotide-binding protein of the G protein gamma family. Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Protein type: G protein, heterotrimeric gamma; G protein, heterotrimeric; G protein. Chromosomal Location of Human Ortholog: 1p31.3. Cellular Component: plasma membrane; heterotrimeric G-protein complex; actin filament. Molecular Function: signal transducer activity; phosphate binding; PDZ domain binding. Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; energy reserve metabolic process; response to lipopolysaccharide; cerebral cortex development; signal transduction