product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-MERTK Antibody
catalog :
MBS820356
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of MERTK expression in Jurkat (A), HeLa (B), Raw264.7 (C), H9C2 (D) whole cell lysates.
product information
catalog number :
MBS820356
products type :
Antibody
products full name :
Anti-MERTK Antibody
products short name :
[MERTK]
products name syn :
[MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK]
other names :
[tyrosine-protein kinase Mer; Tyrosine-protein kinase Mer; tyrosine-protein kinase Mer; STK kinase; proto-oncogene c-Mer; MER receptor tyrosine kinase; receptor tyrosine kinase MerTK; c-mer proto-oncogene tyrosine kinase; MER proto-oncogene, tyrosine kinase; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK]
products gene name :
[MERTK]
other gene names :
[MERTK; MERTK; MER; RP38; c-Eyk; c-mer; Tyro12; MER]
uniprot entry name :
MERTK_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
999
specificity :
Recognizes endogenous levels of MERTK protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info1 :
Entrez Gene: 10461 (Human); 17289 (Mouse); 65037 (Rat). SwissProt: Q12866 (Human); Q60805 (Mouse); P57097 (Rat)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MERTK. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to MERTK
ncbi gi num :
66932918
ncbi acc num :
NP_006334.2
ncbi gb acc num :
NM_006343.2
uniprot acc num :
Q12866
ncbi mol weight :
110,249 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); Hemostasis Pathway (106028)
ncbi summary :
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
uniprot summary :
Mer: a proto-oncogene receptor tyrosine-protein kinase of the Axl family. Binds several ligands including LGALS3, Tubby, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. Protein type: Oncoprotein; Kinase, protein; Protein kinase, TK; EC 2.7.10.1; Protein kinase, tyrosine (receptor); Membrane protein, integral; TK group; Axl family. Chromosomal Location of Human Ortholog: 2q14.1. Cellular Component: extracellular space; photoreceptor outer segment; integral to plasma membrane; cytoplasm; plasma membrane. Molecular Function: protein binding; transmembrane receptor protein tyrosine kinase activity; ATP binding. Biological Process: negative regulation of lymphocyte activation; platelet activation; peptidyl-tyrosine phosphorylation; vagina development; protein amino acid phosphorylation; phagocytosis; cell surface receptor linked signal transduction; cell-cell signaling; retina development in camera-type eye; natural killer cell differentiation; positive regulation of phagocytosis; protein kinase B signaling cascade; spermatogenesis; blood coagulation; leukocyte migration; apoptotic cell clearance; secretion by cell. Disease: Retinitis Pigmentosa 38
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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