product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-ARP3 Antibody
catalog :
MBS820231
quantity :
0.03 mL
price :
155 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, chicken, cow, zebrafish
application :
western blot
more info or order :
image
image 1 :
Western blot analysis of ARP3 expression in A549 (A), Jurkat (B), HeLa (C), A431 (D) whole cell lysates.
product information
catalog number :
MBS820231
products type :
Antibody
products full name :
Anti-ARP3 Antibody
products short name :
[ARP3]
products name syn :
[ARP3; Actin-related protein 3; Actin-like protein 3]
other names :
[actin-related protein 3 isoform 1; Actin-related protein 3; actin-related protein 3; actin-like protein 3; ARP3 actin-related protein 3 homolog (yeast); Actin-like protein 3]
products gene name :
[ACTR3]
other gene names :
[ACTR3; ACTR3; ARP3; ARP3]
uniprot entry name :
ARP3_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Bovine, Chicken, Dog, Pig, Rabbit, Zebrafish
sequence length :
418
specificity :
Recognizes endogenous levels of ARP3 protein.
purity :
The antibody was purified by immunogen affinity chromatography.
form :
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB (1/500 - 1/1000)
image1 heading :
Western Blot (WB)
other info2 :
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ARP3. The exact sequence is proprietary.
products description :
Rabbit polyclonal antibody to ARP3
ncbi gi num :
5031573
ncbi acc num :
NP_005712.1
ncbi gb acc num :
NM_005721.4
uniprot acc num :
P61158
ncbi pathways :
Axon Guidance Pathway (105688); B Cell Receptor Signaling Pathway (198909); CDC42 Signaling Events Pathway (137994); Developmental Biology Pathway (477129); EPH-Ephrin Signaling Pathway (1016174); EPHB-mediated Forward Signaling Pathway (1016176); ErbB1 Downstream Signaling Pathway (138057); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
uniprot summary :
Arp3: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Belongs to the actin family. ARP3 subfamily. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 2q14.1. Cellular Component: Golgi membrane; Arp2/3 protein complex; focal adhesion; hemidesmosome; membrane; lamellipodium; excitatory synapse; podosome; actin filament; intercellular junction; cytosol; actin cytoskeleton. Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; ATP binding. Biological Process: positive regulation of filopodium formation; axon guidance; meiotic chromosome movement towards spindle pole; regulation of myosin II filament assembly or disassembly; establishment and/or maintenance of cell polarity; positive regulation of dendrite morphogenesis; cytokinesis after meiosis; response to carbohydrate stimulus; spindle localization; response to antibiotic; asymmetric cell division; ephrin receptor signaling pathway; innate immune response; cell motility
size1 :
0.03 mL
price1 :
155 USD
size2 :
0.1 mL
price2 :
220
size3 :
0.2 mL
price3 :
295
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
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