Anti-VAChT antibody | MyBioSource MBS802474 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-VAChT antibody

catalog :

MBS802474

quantity :

0.1 mg

price :

390 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[S6-38]

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody at 1:1000.

product information

catalog number :

MBS802474

products type :

Antibody

products full name :

Anti-VAChT antibody

products short name :

[VAChT]

products name syn :

[Vesicular Acetylcholine Transporter; MGC12716; rVAT; Slc18a3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3]

other names :

[vesicular acetylcholine transporter; Vesicular acetylcholine transporter; vesicular acetylcholine transporter; solute carrier family 18 member 3; solute carrier family 18, member 3; solute carrier family 18 (vesicular acetylcholine), member 3; solute carrier family 18 (vesicular acetylcholine transporter), member 3; Solute carrier family 18 member 3]

other gene names :

[SLC18A3; SLC18A3; VACHT; VACHT; VAChT]

uniprot entry name :

VACHT_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

[S6-38]

host :

Mouse

reactivity :

Human, Mouse, Rat

sequence length :

532

specificity :

Detects ~56kDa

purity :

Protein G purified

concentration :

1mg/mL

storage stability :

Store at -20°C; 1 year+; Avoid freeze/thaw cycles. Shipping: Blue Ice or 4°C

tested application :

Immunohistochemistry (IHC), Western Blot (WB)

app notes :

WB (1:1000). IHC (1:200). optimal dilutions for assays should be determined by the end user.

image1 heading :

Western Blot (WB)

other info1 :

Immunogen: Synthetic peptide amino acids 521-532 of human VAChT. Certificate of Analysis: A dilution of 1:50-1:200 was sufficient for detection of VAChT Transporter in rat brain using immunohistochemistry analysis and goat anti-mouse IgG:HRP as the secondary antibody.

other info2 :

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. Cellular Localization: Membrane. Research Area(s): Neuroscience; Cell Structure; Pre-Synaptic Markers; Pumps/Transporters; Neurotransmitter Transporters

products categories :

Transporters

products description :

VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.

products references :

1. Erickson J.D., Varoqui H. (2000) FASEB J. 14(15): 2450-2458. 2. Weihe E., Tao-Cheng J.H., Schafer M.K., Erickson J.D., Eiden L.E. (1996) Proc Natl Acad Sci USA. 93(8): 3547-3552.

ncbi gi num :

118582257

ncbi acc num :

NP_003046.2

ncbi gb acc num :

NM_003055.2

uniprot acc num :

Q16572

ncbi mol weight :

~56kDa

ncbi pathways :

Acetylcholine Neurotransmitter Release Cycle Pathway (106525); Cholinergic Synapse Pathway (217716); Neuronal System Pathway (106513); Neurotransmitter Release Cycle Pathway (106518); Synaptic Vesicle Pathway (672457); Synaptic Vesicle Cycle Pathway (373900); Synaptic Vesicle Cycle Pathway (373890); Transmission Across Chemical Synapses Pathway (106516)

ncbi summary :

This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]

uniprot summary :

SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: acetylcholine transmembrane transporter activity. Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion

size1 :

0.1 mg

price1 :

390 USD

more info or order :

MyBioSource product webpage