antibody

GFAP Mouse Monoclonal

MBS769660

0.1 mg

290 USD

monoclonal

mouse

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry

Antibody

GFAP Mouse Monoclonal

[GFAP]

[FLJ45472, GFAP]

[glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein]

[GFAP]

[GFAP; GFAP; ALXDRD; GFAP]

GFAP_HUMAN

Monoclonal

IgG1

Mouse

Human, Mouse , Rat; other species are not tested.

432

Please decide the specificity by homology

>=95% as determined by SDS-PAGE. Protein A+G purification

Liquid. PBS with 0.02% sodium azide and 50% glycerol pH 7.3

-20°C for 24 months (Avoid repeated freeze / thaw cycles.)

ELISA, WB, IHC.

WB : 1:5000-1:50000. IHC : 1:500-1:10000. IF : 1:50-1:500

Immunohistochemistry(IHC)

SDS-PAGE

Immunogen: Glial fibrillary acidic protein

Calculated MW: 50 kDa

GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

251802

AAB22581.1

Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (1269499); Signal Transduction Pathway (1269379); Signaling By ERBB4 Pathway (1269496); Spinal Cord Injury Pathway (739007)

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: cytoplasm; cytosol; intermediate filament; intermediate filament cytoskeleton; lysosome; membrane; myelin sheath. Molecular Function: glycoprotein binding; integrin binding; kinase binding; protein binding; structural constituent of cytoskeleton. Biological Process: astrocyte development; Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; intermediate filament organization; neurite regeneration; regulation of neurotransmitter uptake; regulation of protein complex assembly; response to wounding. Disease: Alexander Disease

0.1 mg

290 USD