product summary
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company name :
MyBioSource
product type :
antibody
product name :
FNDC5 Rabbit Polyclonal
catalog :
MBS769410
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS769410 image 1
Immunohistochemistry of paraffin-embedded human skeletal muscle slide using MBS769410( FNDC5 Antibody) at dilution of 1:50
image 2 :
MyBioSource MBS769410 image 2
mouse placenta tissue were subjected to SDS PAGE followed by western blot with MBS769410 (FNDC5 antibody) at dilution of 1:1000
product information
catalog number :
MBS769410
products type :
Antibody
products full name :
FNDC5 Rabbit Polyclonal
products short name :
[FNDC5]
products name syn :
[FNDC5, FRCP2, Irisin]
other names :
[fibronectin type III domain-containing protein 5 isoform 2 preproprotein; Fibronectin type III domain-containing protein 5; fibronectin type III domain-containing protein 5; fibronectin type III domain containing 5; Fibronectin type III repeat-containing protein 2]
products gene name :
[FNDC5]
other gene names :
[FNDC5; FNDC5; FRCP2; irisin; FRCP2]
uniprot entry name :
FNDC5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse; other species are not tested.
sequence length :
212
specificity :
Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid
storage stability :
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
WB : 1:200-1:2000. IP :1:200-1:100. IHC : 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: Fibronectin type III domain containing 5. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
other info2 :
Calculated MW: 20 kDa
products description :
Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
ncbi gi num :
511094000
ncbi acc num :
NP_715637.2
ncbi gb acc num :
NM_153756.2
ncbi summary :
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
uniprot summary :
FNDC5: Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p35.1. Cellular Component: endoplasmic reticulum; extracellular region; integral to membrane; peroxisomal membrane; plasma membrane. Molecular Function: hormone activity. Biological Process: response to muscle activity
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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