product summary
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company name :
MyBioSource
product type :
antibody
product name :
EML1 Rabbit Polyclonal
catalog :
MBS768988
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunofluorescent analysis of HepG2 cells, using EML1 antibody MBS768988 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
image 2 :
HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768988 (EML1 antibody) at dilution of 1:300
product information
catalog number :
MBS768988
products type :
Antibody
products full name :
EML1 Rabbit Polyclonal
products short name :
[EML1]
products name syn :
[EML1, EMAP1, EMAP, ELP79, EMAPL1]
other names :
[echinoderm microtubule-associated protein-like 1 isoform a; Echinoderm microtubule-associated protein-like 1; echinoderm microtubule-associated protein-like 1; echinoderm microtubule associated protein like 1]
products gene name :
[EML1]
other gene names :
[EML1; EML1; EMAP; ELP79; EMAPL; HuEMAP; EMAP1; EMAPL; EMAPL1; EMAP-1; HuEMAP-1]
uniprot entry name :
EMAL1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
sequence length :
834
specificity :
human, Mouse, rat; other species are not tested. Please decide the specificity by homology
purity :
Purity: >=95% as determined by SDS-PAGE. Purification: Immunogen Affinity Purified
form :
Liquid
storage stability :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
WB : 1:500-1:2000. IF : 1:10-1:100
image1 heading :
Immunofluorescent
image2 heading :
SDS-PAGE
other info1 :
. Calculated MW: 90kD . Immunogen: Echinoderm microtubule associated protein like 1
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
products description :
Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role
in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division.
Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal
brain development. Does not affect neuron migration per se (By similarity).
ncbi gi num :
56790932
ncbi acc num :
NP_001008707.1
ncbi gb acc num :
NM_001008707.1
uniprot acc num :
O00423
ncbi summary :
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
EML1: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Belongs to the WD repeat EMAP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Microtubule-binding; Cytoskeletal. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: cytosol; microtubule; microtubule associated complex; perinuclear region of cytoplasm. Molecular Function: calcium ion binding; microtubule binding; protein binding; tubulin binding. Biological Process: brain development; hemopoietic progenitor cell differentiation; microtubule cytoskeleton organization and biogenesis; mitotic spindle organization and biogenesis; neuroblast proliferation
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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