catalog number :
MBS768965
products full name :
ELAVL2 Rabbit Polyclonal
products short name :
[ELAVL2]
products name syn :
[ELAV like neuronal protein 1, ELAV like protein 2, ELAV2, ELAVL2, HELN1, HELN1, Hu antigen B, HUB]
other names :
[ELAV-like protein 2 isoform b; ELAV-like protein 2; ELAV-like protein 2; ELAV like neuron-specific RNA binding protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1]
products gene name :
[ELAVL2]
other gene names :
[ELAVL2; ELAVL2; HUB; HELN1; HEL-N1; HUB; HuB]
uniprot entry name :
ELAV2_HUMAN
reactivity :
Human, Mouse, Rat, Zebrafish
specificity :
Human, Mouse ,Rat; other species are not tested. Please decide the specificity by homology
purity :
Purification: Immunogen affinity purified. Purity: > or = 95% as determined by SDS-PAGE
storage stability :
-20 degree C for 24 months (Avoid repeated freeze/thaw cycles.)
tested application :
ELISA, WB, IHC, IP
app notes :
WB : 1:1000-1:10000. IP : 1:500-1:5000. IHC : 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
products description :
Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
ncbi acc num :
NP_001164666.1
ncbi gb acc num :
NM_001171195.1
ncbi pathways :
Gene Expression Pathway (1269649); Processing Of Capped Intron-Containing Pre-mRNA Pathway (1269688); MRNA Splicing Pathway (1269689); MRNA Splicing - Major Pathway (1269690)
ncbi summary :
The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
uniprot summary :
ELAVL2: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding. Chromosomal Location of Human Ortholog: 9p21. Cellular Component: nucleoplasm. Molecular Function: mRNA 3'-UTR binding; nucleotide binding; protein binding. Biological Process: nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent