product summary
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company name :
MyBioSource
product type :
antibody
product name :
EIF4A2 Rabbit Polyclonal
catalog :
MBS768949
quantity :
0.1 mg
price :
265 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human ovary tumor using MBS768949 (EIF4A2 antibody) at dilution of 1:100
image 2 :
Jurkat cells were subjected to SDS PAGE followed by western blot with MBS768949 (EIF4A2 antibody) at dilution of 1:400
product information
catalog number :
MBS768949
products type :
Antibody
products full name :
EIF4A2 Rabbit Polyclonal
products short name :
[EIF4A2]
products name syn :
[BM 010; DDX2B; eIF 4A II; EIF4A; eIF4A II; EIF4A2; EIF4F]
other names :
[eukaryotic initiation factor 4A-II; Eukaryotic initiation factor 4A-II; eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase eIF4A-2]
products gene name :
[EIF4A2]
other gene names :
[EIF4A2; EIF4A2; DDX2B; EIF4A; EIF4F; BM-010; eIF4A-II; eIF-4A-II; DDX2B; EIF4F; eIF-4A-II; eIF4A-II]
uniprot entry name :
IF4A2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
407
specificity :
Other species are not tested. Please decide the specificity by homology.
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
storage stability :
-20 degree C for 24 months (Avoid repeated freeze/thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
WB: 1:200-1:1000. IP: 1:500-1:1000. IHC: 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: Eukaryotic translation initiation factor 4A, isoform 2
products description :
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
ncbi gi num :
83700235
ncbi acc num :
NP_001958.2
ncbi gb acc num :
NM_001967.3
uniprot acc num :
Q14240
ncbi mol weight :
47kd
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (1268683); Antiviral Mechanism By IFN-stimulated Genes Pathway (1269316); Cap-dependent Translation Initiation Pathway (1268680); Cytokine Signaling In Immune System Pathway (1269310); Deadenylation Of MRNA Pathway (1269713); Deadenylation-dependent MRNA Decay Pathway (1269712); Eukaryotic Translation Initiation Pathway (1268679); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (1268686); Gene Expression Pathway (1269649); ISG15 Antiviral Mechanism Pathway (1269317)
uniprot summary :
EIF4A2: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. Belongs to the DEAD box helicase family. eIF4A subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Translation; EC 3.6.4.13; Translation initiation; Helicase; RNA-binding. Chromosomal Location of Human Ortholog: 3q28. Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; perinuclear region of cytoplasm. Molecular Function: ATP binding; ATP-dependent RNA helicase activity; ATPase activity; helicase activity; protein binding; translation initiation factor activity. Biological Process: poly(A) tail shortening; regulation of translational initiation; RNA secondary structure unwinding; translational initiation; viral reproduction
size1 :
0.1 mg
price1 :
265 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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