catalog number :
MBS768430
products full name :
Cytokeratin 15 Rabbit Polyclonal
products short name :
[Cytokeratin 15]
products name syn :
[CK 15, CK15, Cytokeratin 15, K15, K1CO, keratin 15, KRT15, KRTB]
other names :
[cytokeratin associated protein; Leucine-rich repeat-containing protein 26; BK channel auxiliary gamma subunit LRRC26; Cytokeratin-associated protein in cancer]
other gene names :
[LRRC26; CAPC]
uniprot entry name :
LRC26_HUMAN
reactivity :
Human, Mouse, Rat, other species are not tested.
specificity :
Please decide specifity by homology.
purity :
Purity: >=95% as determined by SDS-PAGE. Purification: Immunogen Affinity Purified
storage stability :
Store at -20°for 24 months (Avoid repeated freeze/thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
app notes :
WB: 1:200-1:2000. IP: 1:200-1:2000. IHC: 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: Keratin 15
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Calculated MW: 49 kDa
products description :
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8,and the hair keratins, Hb1–Hb6. Keratin 15 is a type I cytokeratin. It is found in some progenitor basal cells within complex epithelia.
ncbi acc num :
ABC79623.1
uniprot summary :
LRRC26: Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low- voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: cytoplasm; cytoskeleton; voltage-gated potassium channel complex. Molecular Function: potassium channel regulator activity; protein binding. Biological Process: ion transport