catalog number :
MBS768421
products full name :
Cytoglobin Mouse Monoclonal
products short name :
[Cytoglobin]
products name syn :
[CYGB, cytoglobin, HGB, Histoglobin]
other names :
[cytoglobin; Cytoglobin; cytoglobin; cytoglobin; Histoglobin; HGb; Stellate cell activation-associated protein]
other gene names :
[CYGB; CYGB; HGB; STAP; STAP; HGb]
uniprot entry name :
CYGB_HUMAN
reactivity :
Human, Mouse
specificity :
Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Protein A+G purification
storage stability :
-20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
image1 heading :
Immunohistochemistry
image2 heading :
Immunofluorescent
image3 heading :
SDS-PAGE
other info1 :
Immunogen: Cytoglobin
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
ncbi acc num :
NP_599030.1
ncbi gb acc num :
NM_134268.4
ncbi pathways :
Metabolism Pathway (1269956); Metabolism Of Nitric Oxide Pathway (1270115); ENOS Activation Pathway (1270117); ENOS Activation And Regulation Pathway (1270116)
ncbi summary :
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]
uniprot summary :
CYGB: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Belongs to the globin family. Chromosomal Location of Human Ortholog: 17q25. Cellular Component: cell soma; cytosol; neuron projection. Molecular Function: catalase activity; fatty-acid peroxidase activity; heme binding; iron ion binding; nitric oxide dioxygenase activity; oxygen binding; oxygen transporter activity; peroxidase activity; protein binding. Biological Process: fatty acid oxidation; negative regulation of collagen biosynthetic process; oxygen transport; regulation of nitric-oxide synthase activity; response to hypoxia; response to oxidative stress