product summary
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company name :
MyBioSource
product type :
antibody
product name :
CX3CL1 Mouse Monoclonal
catalog :
MBS768321
quantity :
0.1 mg
price :
265 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[5D1]
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS768321 image 1
Immunohistochemistry of paraffin-embedded human brain tissue slide using MBS768321 (CX3CL1 Antibody) at dilution of 1:200.
image 2 :
MyBioSource MBS768321 image 2
PC-3 cells were subjected to SDS PAGE followed by western blot with MBS768321 (CX3CL1 antibody) at dilution of 1:1000.
product information
catalog number :
MBS768321
products type :
Antibody
products full name :
CX3CL1 Mouse Monoclonal
products short name :
[CX3CL1]
products name syn :
[FKN, NTT, SCYD1]
other names :
[CX3CL1; CX3CL1 protein; fractalkine; C-X3-C motif chemokine ligand 1; CX3CL1 protein]
products gene name :
[CX3CL1]
other gene names :
[CX3CL1; CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin]
uniprot entry name :
Q6I9S9_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
[5D1]
host :
Mouse
reactivity :
Human; other species are not tested.
specificity :
Please decide the specificity by homology.
purity :
> 95% as determined by SDS-PAGE/Protein A+G purification
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
Store at -20°C for 24 months. (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: Chemokine (C-X3-C motif) ligand 1
products description :
Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1(PubMed:23125415, PubMed:9931005, PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site(site 1) in integrins. In the absence of CX3CR1, binds to a second site(site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1(PubMed:23125415, PubMed:24789099). The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium(PubMed:9024663, PubMed:9177350).
ncbi gi num :
48146969
ncbi acc num :
CAG33707.1
uniprot acc num :
Q6I9S9
ncbi mol weight :
90 kDa
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1269547); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Direct P53 Effectors Pathway (137939); GPCR Ligand Binding Pathway (1269544); Peptide Ligand-binding Receptors Pathway (1269546); Signal Transduction Pathway (1269379)
size1 :
0.1 mg
price1 :
265 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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