product summary
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company name :
MyBioSource
product type :
antibody
product name :
CES3 Rabbit Polyclonal
catalog :
MBS767849
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human colon cancer using MBS767849 (CES3 antibody) at dilution of 1:100
image 2 :
HeLa cells were subjected to SDS PAGE followed by western blot with MBS767849 (CES3 antibody) at dilution of 1:500
product information
catalog number :
MBS767849
products type :
Antibody
products full name :
CES3 Rabbit Polyclonal
products short name :
[CES3]
products name syn :
[carboxylesterase 3, CES3, ES31]
other names :
[carboxylesterase 3 isoform 2; Carboxylesterase 3; carboxylesterase 3; carboxylesterase 3; Liver carboxylesterase 31 homolog]
products gene name :
[CES3]
other gene names :
[CES3; CES3; ES31]
uniprot entry name :
EST3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse; other species are not tested.
sequence length :
568
specificity :
Please decide the specificity by homology
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500-1:2000. IHC: 1:20-1:200. IF: 1:50-1:500
image1 heading :
Immunohistochemistry (IHC) (IHC)
image2 heading :
Western Blot(WB)
other info1 :
Immunogen: carboxylesterase 3
other info2 :
Purification: Immunogen affinity purified. Purity: > 95% as determined by SDS-PAGE
products description :
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.Shows low catalytic efficiency for hydrolysis of CPT-11(7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
ncbi gi num :
297747275
ncbi acc num :
NP_001172106.1
ncbi gb acc num :
NM_001185177.1
uniprot acc num :
Q6UWW8
ncbi mol weight :
60-62 kDa
ncbi pathways :
E2F Transcription Factor Network Pathway (137934)
ncbi summary :
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010]
uniprot summary :
CES3: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)- 1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. Belongs to the type-B carboxylesterase/lipase family. Protein type: Endoplasmic reticulum; Secreted, signal peptide; EC 3.1.1.1; Secreted; Hydrolase. Chromosomal Location of Human Ortholog: 16q22.1. Cellular Component: endoplasmic reticulum lumen; extracellular space. Biological Process: metabolic process
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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