product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD63 Rabbit Polyclonal
catalog :
MBS767722
quantity :
0.1 mg
price :
265 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human lung cancer using MBS767722 ( CD63 Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
image 2 :
Mouse spleen were subjected to SDS PAGE followed by western blot with MBS767722 ( CD63 Antibody) at dilution of 1:1000
product information
catalog number :
MBS767722
products type :
Antibody
products full name :
CD63 Rabbit Polyclonal
products short name :
[CD63]
products name syn :
[MLA1, TSPAN30]
other names :
[CD63 antigen isoform D; CD63 antigen; CD63 antigen; CD63 molecule; Granulophysin; Lysosomal-associated membrane protein 3; LAMP-3; Melanoma-associated antigen ME491; OMA81H; Ocular melanoma-associated antigen; Tetraspanin-30; Tspan-30; CD_antigen: CD63]
products gene name :
[CD63]
other gene names :
[CD63; CD63; MLA1; ME491; LAMP-3; OMA81H; TSPAN30; MLA1; TSPAN30; LAMP-3; Tspan-30]
uniprot entry name :
CD63_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat; other species are not tested.
sequence length :
156
specificity :
Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
storage stability :
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Testing Data (TD)
other info1 :
Immunogen: CD63 molecule. Calculated MW: 53 kDa
products description :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
ncbi gi num :
383872547
ncbi acc num :
NP_001244330.1
ncbi gb acc num :
NM_001257401.1
ncbi pathways :
Hemostasis Pathway (1269340); Lysosome Pathway (99052); Lysosome Pathway (96865); Platelet Activation, Signaling And Aggregation Pathway (1269350); Platelet Degranulation Pathway (1269367); Proteoglycans In Cancer Pathway (782000); Proteoglycans In Cancer Pathway (782054); Response To Elevated Platelet Cytosolic Ca2+ Pathway (1269365)
ncbi summary :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
uniprot summary :
CD63: This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. Belongs to the tetraspanin (TM4SF) family. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12q12-q13. Cellular Component: cell surface; endosome membrane; extracellular space; integral to plasma membrane; intrinsic to plasma membrane; late endosome membrane; lysosomal membrane; melanosome; plasma membrane; platelet dense granule membrane; protein complex. Molecular Function: protein binding; protein complex binding. Biological Process: cell migration; cell-matrix adhesion; epithelial cell differentiation; pigment granule maturation; platelet degranulation; positive regulation of cell adhesion; positive regulation of receptor internalization; protein transport
size1 :
0.1 mg
price1 :
265 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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