product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD27 Rabbit Polyclonal
catalog :
MBS767685
quantity :
0.1 mg
price :
265 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, flow cytometry, FACS, enzyme immunoassay
more info or order :
image
image 1 :
1X10^6 Raji cells were stained with 0.2ug CD27 antibody (MBS767685, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.
image 2 :
Jurkat cells were subjected to SDS PAGE followed by western blot with MBS767685 (CD27 antibody) at dilution of 1:600
product information
catalog number :
MBS767685
products type :
Antibody
products full name :
CD27 Rabbit Polyclonal
products short name :
[CD27]
products name syn :
[CD27, CD27 antigen, CD27 molecule, CD27L receptor, S152, T cell activation antigen CD27, T14, TNFRSF7, Tp55]
other names :
[CD27 antigen; CD27 antigen; CD27 antigen; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27]
products gene name :
[CD27]
other gene names :
[CD27; CD27; T14; S152; Tp55; TNFRSF7; S152. LPFS2; TNFRSF7]
uniprot entry name :
CD27_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
260
specificity :
Other species are not tested. Please decide the specificity by homology
purity :
Purification: Immunogen affinity purified. Purity: > or =95% as determined by SDS-PAGE
form :
Liquid
storage stability :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
app notes :
WB: 1:500-1:1000
image1 heading :
Flow Cytometry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: CD27 molecule
ncbi gi num :
4507587
ncbi acc num :
NP_001233.1
ncbi gb acc num :
NM_001242.4
uniprot acc num :
P26842
ncbi mol weight :
50 kDa
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Immune System Pathway (1269170); TNFR2 Non-canonical NF-kB Pathway (1269329); TNFs Bind Their Physiological Receptors Pathway (1269332)
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
CD27: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. Protein type: Receptor, cytokine; Apoptosis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: external side of plasma membrane; extracellular region; integral to plasma membrane; neuron projection; nucleus; plasma membrane. Molecular Function: caspase inhibitor activity; protein binding; transmembrane receptor activity; tumor necrosis factor receptor activity. Biological Process: brain development; cell surface receptor linked signal transduction; immune response; immunoglobulin mediated immune response; induction of apoptosis via death domain receptors; inflammatory response; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of B cell differentiation; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; regulation of cell proliferation; release of cytoplasmic sequestered NF-kappaB; response to ethanol; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway. Disease: Lymphoproliferative Syndrome 2
size1 :
0.1 mg
price1 :
265 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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