catalog number :
MBS767403
products full name :
CACNA1B Rabbit Polyclonal
products short name :
[CACNA1B]
products name syn :
[BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, CACNN, Cav2.2]
products gene name :
[CACNA1B]
reactivity :
Human, Mouse, Rat; other species are not tested.
specificity :
Please decide the specificity by homology.
purity :
> 95% as determined by SDS-PAGE; Immunogen affinity purified
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
Store at -20°C for 24 months. (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB: 1:200-1:1000; IHC: 1:50-1:500
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Western Blot (WB)
other info1 :
Immunogen: calcium channel, voltage-dependent, N type, alpha 1B subunit
products description :
Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
ncbi mol weight :
Observed MW: 262 kDa