catalog number :
MBS7605982
products full name :
ZnT7 Rabbit Polyclonal
products short name :
[ZnT7]
other names :
[zinc transporter 7; Zinc transporter 7; zinc transporter 7; solute carrier family 30 member 7; Solute carrier family 30 member 7; Znt-like transporter 2]
products gene name :
[ZnT7]
other gene names :
[SLC30A7; SLC30A7; ZNT7; ZnT-7; ZnTL2; ZNT7; ZNTL2; ZnT-7]
uniprot entry name :
ZNT7_HUMAN
reactivity :
Human, Mouse, Rat. Other species are not tested.
specificity :
Please decide specifity by homology.
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
storage stability :
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Western Blot (WB) 1:200-1:2000. Immunohistochemistry (IHC) 1:20-200. Immunoflourescence (IF)1:20-200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Testing Data (TD)
other info1 :
Immunogen: Solute carrier family 30 (zinc transporter), member 7. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
other info2 :
Calculated MW: 65 kDa
ncbi acc num :
NP_001138356.1
ncbi gb acc num :
NM_001144884.1
ncbi pathways :
Insulin Processing Pathway (1268747); Metabolism Of Proteins Pathway (1268677); Metal Ion SLC Transporters Pathway (1269930); Peptide Hormone Metabolism Pathway (1268746); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1269923); Zinc Efflux And Compartmentalization By The SLC30 Family Pathway (1269932); Zinc Transporters Pathway (1269931)
ncbi summary :
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
uniprot summary :
SLC30A7: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. Protein type: Transporter, SLC family; Membrane protein, multi-pass; Vesicle; Membrane protein, integral; Transporter. Chromosomal Location of Human Ortholog: 1p21.2. Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; Golgi apparatus; integral to membrane; membrane; perinuclear region of cytoplasm; vesicle. Molecular Function: zinc ion transmembrane transporter activity. Biological Process: response to zinc ion; sequestering of zinc ion