product summary
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company name :
MyBioSource
product type :
antibody
product name :
UPK1A Rabbit Polyclonal
catalog :
MBS7605506
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS7605506
products type :
Antibody
products full name :
UPK1A Rabbit Polyclonal
products short name :
[UPK1A]
products name syn :
[Tetraspanin 21, Tspan 21, TSPAN21, UP1A, UPIA, UPK1A, UPKA,uroplakin 1A, Uroplakin Ia]
other names :
[uroplakin-1a isoform 2; Uroplakin-1a; uroplakin-1a; uroplakin 1A; Tetraspanin-21; Tspan-21; Uroplakin Ia; UPIa; UPKa]
products gene name :
[UPK1A]
other gene names :
[UPK1A; UPK1A; UP1A; UPIA; UPKA; TSPAN21; TSPAN21; UP1a; Tspan-21; UPIa; UPKa]
uniprot entry name :
UPK1A_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse; other species are not tested.
sequence length :
273
specificity :
Please decide specifity by homology
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid
storage stability :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA, IHC, IP
app notes :
IHC: 1:20-1:200. IP: 1:200-1:1000
other info1 :
Immunogen: Uroplakin 1A. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Calculated MW: 29 kDa
products description :
Component of the asymmetric unit membrane(AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions(By similarity).
ncbi gi num :
527498307
ncbi acc num :
NP_001268372.1
ncbi gb acc num :
NM_001281443.1
ncbi summary :
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
uniprot summary :
UPK1A: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. Belongs to the tetraspanin (TM4SF) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.13. Cellular Component: apical plasma membrane; endoplasmic reticulum; integral to membrane; integral to plasma membrane; plasma membrane. Molecular Function: monosaccharide binding; protein homodimerization activity. Biological Process: cell surface receptor linked signal transduction; epithelial cell differentiation; protein oligomerization
size1 :
0.1 mg
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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