catalog number :
MBS7605500
products full name :
uPA Rabbit Polyclonal
products short name :
[uPA]
products name syn :
[ATF; PLAU; U plasminogen activator; uPA; URK]
products gene name :
[uPA]
reactivity :
Human, Mouse, Rat
specificity :
Other species are not tested. Please decide the specificity by homology
purity :
Purification: Immunogen affinity purified. Purity: > = 95% as determined by SDS-PAGE
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
app notes :
WB: 1:500-1:1000. IHC: 1:20-1:200. IF: 1:20-1:200. IP: 1:500-1:2000
image1 heading :
Immunohistochemistry
image2 heading :
Immunofluorescent
image3 heading :
SDS-PAGE
other info1 :
Immunogen: plasminogen activator, urokinase
products description :
PLAU (Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD).