catalog number :
MBS7605056
products full name :
TNFR1 Mouse Monoclonal
products short name :
[TNFR1]
products name syn :
[anti-TNFR1 antibody; CD120a, FPF, p55, p55 R, p60, TBP1, TBPI, TNF R, TNF R I, TNF R1, TNF R55, TNF Receptor 1, TNF Receptor I, TNF RI, TNFAR, TNFR I, TNFR1, TNFR55, TNFR60, TNFRSF1A]
products gene name :
[TNFR1]
reactivity :
Human, Mouse
specificity :
Human, Mouse; other species are not tested. Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Protein A+G purification
storage stability :
Store at -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
app notes :
WB : 1:500-1:5000. IHC : 1:50-1:500
image1 heading :
Immunohistochemistry
image2 heading :
Testing Data
image3 heading :
SDS PAGE
other info1 :
Immunogen: Tumor necrosis factor receptor superfamily, member 1A. Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
products description :
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.