product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
SIM2 Rabbit Polyclonal
catalog :
MBS7604102
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS7604102 image 1
HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7604102 (SIM2 antibody) at dilution of 1:1000
product information
catalog number :
MBS7604102
products type :
Antibody
products full name :
SIM2 Rabbit Polyclonal
products short name :
[SIM2]
products name syn :
[bHLHe15, SIM, SIM2, Single minded homolog 2]
other names :
[single-minded homolog 2 long isoform; Single-minded homolog 2; single-minded homolog 2; single-minded family bHLH transcription factor 2; Class E basic helix-loop-helix protein 15; bHLHe15]
products gene name :
[SIM2]
other gene names :
[SIM2; SIM2; SIM; bHLHe15; HMC13F06; HMC29C01; BHLHE15; bHLHe15]
uniprot entry name :
SIM2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat; other species are not tested.
sequence length :
667
specificity :
Please deide specifity by homology.
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid
storage stability :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
app notes :
WB: 1:500-1:2000. IP: 1:500-1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Single-minded homolog 2 (Drosophila)
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development.
ncbi gi num :
4827004
ncbi acc num :
NP_005060.1
ncbi gb acc num :
NM_005069.4
ncbi summary :
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
uniprot summary :
SIM2: Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; DNA-binding. Chromosomal Location of Human Ortholog: 21q22.13. Cellular Component: nucleoplasm. Molecular Function: DNA binding; protein heterodimerization activity; transcription factor activity. Biological Process: cell differentiation; embryonic pattern specification; lung development; negative regulation of transcription from RNA polymerase II promoter; nervous system development; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
size1 :
0.1 mg
price1 :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!