product summary
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company name :
MyBioSource
product type :
antibody
product name :
PKM1-specific Rabbit Polyclonal
catalog :
MBS7602727
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using MBS7602727 ( PKM1 Antibody) at dilution of 1:200
image 2 :
Immunofluorescent analysis of HeLa cells using MBS7602727 (PKM1 antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
image 3 :
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS7602727 (PKM1 antibody) at dilution of 1:1000
product information
catalog number :
MBS7602727
products type :
Antibody
products full name :
PKM1-specific Rabbit Polyclonal
products short name :
[PKM1]
products name syn :
[CTHBP, OIP 3, OIP3, Opa interacting protein 3, p58, PK2, PK3, PKM, PKM1, PK-M1, PKM1 pyruvate kinase, muscle, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, TCB, THBP1, Tumor M2 PK]
products gene name :
[PKM1]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
specificity :
Human, Mouse, Rat; other species are not tested. Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid
storage stability :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA, WB, IHC, IP, IF
app notes :
WB : 1:500-1:2000. IP : 1:500-1:2000. IHC : 1:100-1:400. IF : 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
Immunofluorescent
image3 heading :
SDS-PAGE
products description :
Background: PKM, also named as OIP3, PK2, PK3, PKM, p58, THBP1, CTHBP and Tumor M2-PK, belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. It stimulates POU5F1-mediated transcriptional activation. PKM plays a general role in caspase independent cell death of tumor cells. PKM has 2 isoforms named PKM1 and PKM2. By the upstream metabolite fructose-1,6-bisphosphate, PKM1 is a constitutively active enzyme.The primary pyruvate kinase isoform before tumour development is PK-M1; however, the primary isoform from four independent tumours is PK-M2 (PMID:18337823). This antibody is specific to PKM1 isoform.
ncbi acc num :
P14618
ncbi mol weight :
58KD
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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