product summary
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company name :
MyBioSource
product type :
antibody
product name :
PAPD5 Rabbit Polyclonal
catalog :
MBS7602372
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunoprecipitation
more info or order :
image
image 1 :
mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7602372 D(PAPD5 antibody) at dilution of 1:1000
product information
catalog number :
MBS7602372
products type :
Antibody
products full name :
PAPD5 Rabbit Polyclonal
products short name :
[PAPD5]
products name syn :
[PAPD5, Terminal uridylyltransferase 3, TRF4 2, TUTase 3]
other names :
[non-canonical poly(A) RNA polymerase PAPD5 isoform X4; Non-canonical poly(A) RNA polymerase PAPD5; non-canonical poly(A) RNA polymerase PAPD5; PAP associated domain containing 5; PAP-associated domain-containing protein 5; Terminal uridylyltransferase 3; TUTase 3; Topoisomerase-related function protein 4-2; TRF4-2]
products gene name :
[PAPD5]
other gene names :
[PAPD5; PAPD5; TRF4-2; TUTase 3; TRF4-2]
uniprot entry name :
PAPD5_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat; other species are not tested.
sequence length :
693
specificity :
Please decide the specificity by homology.
purity :
>=95% as determined by SDS-PAGE. Immunogen Affinity Purified
form :
Liquid
storage stability :
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA, WB, IP
app notes :
WB: 1:500 - 1:2000
image1 heading :
SDS-PAGE
other info1 :
Immunogen: PAP associated domain containing 5. Calculated MW: 50 kDa, 80kDa
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3
products description :
Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
ncbi gi num :
1034595604
ncbi acc num :
XP_016879044.1
ncbi gb acc num :
XM_017023555.1
uniprot acc num :
Q8NDF8
ncbi pathways :
RNA Degradation Pathway (117291); RNA Degradation Pathway (116127); TRAMP Complex Pathway (413459); TRAMP Complex Pathway (468399)
uniprot summary :
PAPD5: Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Belongs to the DNA polymerase type-B-like family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Transferase; Nucleolus; EC 2.7.7.19. Chromosomal Location of Human Ortholog: 16q12.1. Cellular Component: cytoplasm; nucleolus. Molecular Function: DNA binding; DNA-directed DNA polymerase activity; metal ion binding; polynucleotide adenylyltransferase activity. Biological Process: cell division; mitosis; mRNA processing; rRNA processing
size1 :
0.1 mg
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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