catalog number :
MBS7602297
products full name :
P16-INK4A Rabbit Polyclonal
products short name :
[P16-INK4A]
products name syn :
[ARF,CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, p14, p14ARF, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, P19, TP16]
products gene name :
[P16-INK4A]
reactivity :
Human, Mouse, Rat; other species are not tested.
specificity :
Please decide the specificity by homology
form :
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
Store at -20°C for 24 months (Avoid repeated freeze/thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
app notes :
Recommended dilution:. WB: 1:500-1:5000. IP: 1:500-1:5000. IHC: 1:50-1:500. IF: 1:20-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunoprecipitation (IP)
image3 heading :
Western Blot (WB)
other info1 :
Purification: Immunogen affinity purified. Purity: > 95% as determined by SDS-PAGE. Immunogen: Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
products description :
CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). 10883-1-AP reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma.