catalog number :
MBS7601808
products full name :
anti- NCAM1/CD56 antibody
products short name :
[NCAM1/CD56]
products name syn :
[CD56, MSK39, N CAM 1, NCAM, NCAM 1, NCAM1]
products gene name :
[NCAM1/CD56]
reactivity :
Human, Mouse
specificity :
Human, Mouse; other species are not tested. Please decide the specificity by homology
purity :
>=95% as determined by SDS-PAGE. Protein A+G purification
tested application :
ELISA, WB, IHC
app notes :
WB : 1:1000-1:10000. IHC : 1:200-1:1000
image1 heading :
Immunohistochemistry
image2 heading :
SDS-PAGE
other info1 :
Immunogen: Neural cell adhesion molecule 1
other info2 :
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20 degree C for 24 months (Avoid repeated freeze/thaw cycles.)
products description :
Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurones, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated byalternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described (PMID: 1856291).
ncbi mol weight :
140 kDa