catalog number :
MBS7600621
products full name :
IRF2BP2 Rabbit Polyclonal
products short name :
[IRF2BP2]
products name syn :
[IRF 2 binding protein 2, IRF 2BP2, IRF2BP2]
other names :
[interferon regulatory factor 2-binding protein 2 isoform B; Interferon regulatory factor 2-binding protein 2; interferon regulatory factor 2-binding protein 2; interferon regulatory factor 2 binding protein 2]
products gene name :
[IRF2BP2]
other gene names :
[IRF2BP2; IRF2BP2; IRF-2-binding protein 2; IRF-2BP2]
uniprot entry name :
I2BP2_HUMAN
reactivity :
Human, Mouse; other species are not tested.
specificity :
Please decide the specificity by homology
purity :
Purification: Immunogen affinity purified. Purity: > or = 95% as determined by SDS-PAGE
form :
Liquid. PBS with 0.02% sodium azide and 50% glycerol pH 7.3,
storage stability :
-20°C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
app notes :
WB: 1:1000-1:4000. IP: 1:500-1:1000. IHC: 1:20-1:200. IF: 1:20-1:200
image1 heading :
Immunohistochemistry
image2 heading :
Immunofluorescent
image3 heading :
SDS-PAGE
other info1 :
Immunogen: Interferon regulatory factor 2 binding protein 2
products description :
Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle.
ncbi acc num :
NP_001070865.1
ncbi gb acc num :
NM_001077397.1
ncbi summary :
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
IRF2BP2: Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscle. Belongs to the IRF2BP family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 1q42.3. Cellular Component: cytoplasm; nucleus. Molecular Function: metal ion binding. Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent