antibody

IL-6 Rabbit Polyclonal

MBS7600515

0.1 mg

320 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

Antibody

IL-6 Rabbit Polyclonal

[IL-6]

[B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6]

[interleukin-6; Interleukin-6; interleukin-6; interleukin 6]

[IL-6]

[Il6; Il6; ILg6; Ifnb2; Il-6; IL-6]

IL6_RAT

Polyclonal

IgG

Rabbit

Human, Mouse, Rat; other species are not tested.

211

Please decide the specificity by homology.

> 95% as determined by SDS-PAGE/Immunogen affinity purified

Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3

Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Recommended dilution:. WB: 1:500-1:1000; . IHC: 1:50-1:200;. IF: 1:50-1:200

Immunohistochemistry (IHC)

Immunofluorescence (IF)

Western Blot (WB)

Immunogen: Interleukin 6 (interferon, beta 2)

Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

7549769

NP_036721.1

NM_012589.2

P05231

24 kDa

AGE-RAGE Signaling Pathway In Diabetic Complications (1320189); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); Adipogenesis Pathway (198479); African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Androgen Receptor Signaling Pathway (198529); Cellular Senescence Pathway (1376566); Cellular Responses To Stress Pathway (1376554)

a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 2006]

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().

0.1 mg

320 USD