product summary
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company name :
MyBioSource
product type :
antibody
product name :
IL22RA2 Mouse Monoclonal
catalog :
MBS7600488
quantity :
0.1 mg
price :
320 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using MBS7600488 (IL22RA2 Antibody) at dilution of 1:50
image 2 :
Raji cells were subjected to SDS PAGE followed by western blot with MBS7600488 (IL22RA2 Antibody) at dilution of 1:1000
product information
catalog number :
MBS7600488
products type :
Antibody
products full name :
IL22RA2 Mouse Monoclonal
products short name :
[IL22RA2]
products name syn :
[CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16]
other names :
[interleukin-22 receptor subunit alpha-2 isoform 2; Interleukin-22 receptor subunit alpha-2; interleukin-22 receptor subunit alpha-2; interleukin 22 receptor subunit alpha 2; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; CRF2-10; Cytokine receptor family type 2, soluble 1; CRF2-S1; Interleukin-22-binding protein; IL-22BP; IL22BP; ZcytoR16]
products gene name :
[IL22RA2]
other gene names :
[IL22RA2; IL22RA2; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2; IL-22 receptor subunit alpha-2; IL-22R-alpha-2; IL-22RA2; CRF2-10; CRF2-S1; IL-22BP; IL22BP]
uniprot entry name :
I22R2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
reactivity :
Human, other species are not tested.
sequence length :
231
specificity :
Human; other species are not tested. Please decide the specificity by homology
purity :
Purification: Protein A+G purification. Purity: > = 95% as determined by SDS-PAGE
form :
liquid. PBS with 0.02% sodium azide and 50% glycerol pH 7.3
storage stability :
-20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000. IHC: 1:20-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
SDS PAGE
other info1 :
Immunogen: interleukin 22 receptor, alpha 2
products description :
Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22(in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy.
ncbi gi num :
31317241
ncbi acc num :
NP_851826.1
ncbi gb acc num :
NM_181309.1
ncbi mol weight :
35 kDa
ncbi pathways :
Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Immune System Pathway (1269170); Interleukin-19, 20, 22, 24 Pathway (1383036); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Signaling By Interleukins Pathway (1269318)
ncbi summary :
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
uniprot summary :
IL22RA2: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Belongs to the type II cytokine receptor family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q23.3. Cellular Component: cytosol; extracellular region; extracellular space; integral to membrane; plasma membrane. Molecular Function: interleukin-22 binding; interleukin-22 receptor activity. Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of inflammatory response; regulation of tyrosine phosphorylation of Stat3 protein
size1 :
0.1 mg
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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