catalog number :
MBS756330
products type :
ELISA Kit
products full name :
Rabbit 1, 5-anhydro-D-fructose reductase (AKR1CL2) ELISA Kit
products short name :
1, 5-anhydro-D-fructose reductase (AKR1CL2)
other names :
glutamate decarboxylase 2; Glutamate decarboxylase 2; glutamate decarboxylase 2; GAD-65; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 65 kDa isoform; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
products gene name :
AKR1CL2
other gene names :
GAD2; GAD2; GAD65; GAD65; GAD-65
uniprot entry name :
DCE2_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_001127838.1
ncbi gb acc num :
NM_001134366.1
ncbi mol weight :
65,411 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway 198783!!Alanine, Aspartate And Glutamate Metabolism Pathway 101142!!Alanine, Aspartate And Glutamate Metabolism Pathway 100063!!Biogenic Amine Synthesis Pathway 198793!!Butanoate Metabolism Pathway 83007!!Butanoate Metabolism Pathway 391!!GABA (gamma-Aminobutyrate) Shunt Pathway 413433!!GABA (gamma-Aminobutyrate) Shunt Pathway 468220!!GABA Synthesis Pathway 187175!!GABA Synthesis, Release, Reuptake And Degradation Pathway 187174
ncbi summary :
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]