Rabbit Protease Activated Receptor 1 ELISA Kit | MyBioSource MBS746436 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rabbit Protease Activated Receptor 1 ELISA Kit

catalog :

MBS746436

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS746436

products type :

ELISA Kit

products full name :

Rabbit Protease Activated Receptor 1 ELISA Kit

products short name :

Protease Activated Receptor 1

other names :

proteinase-activated receptor 1; Proteinase-activated receptor 1; proteinase-activated receptor 1; protease-activated receptor 1; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; Thrombin receptor

products gene name :

PAR1

other gene names :

F2R; F2R; TR; HTR; CF2R; PAR1; PAR-1; CF2R; PAR1; TR; PAR-1

uniprot entry name :

PAR1_HUMAN

reactivity :

Rabbit

storage stability :

Store all reagents at 2-8 degree C.

other info1 :

Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Sensitivity: 0.1 ng/mL.

other info2 :

Intended Uses: This PAR-1 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rabbit PAR-1. This ELISA kit for research use only, not for therapeutic or diagnostic applications!

products categories :

Signal Transduction

ncbi gi num :

166362740

ncbi acc num :

NP_001983.2

ncbi gb acc num :

NM_001992.3

ncbi mol weight :

47,441 Da

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Endocytosis Pathway (102279); Endocytosis Pathway (102181); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548)

ncbi summary :

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. [provided by RefSeq, Jul 2008]

uniprot summary :

PAR1: a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development. Protein type: Cell development/differentiation; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: 5q13. Cellular Component: Golgi apparatus; postsynaptic membrane; integral to plasma membrane; early endosome; plasma membrane; extracellular region; caveola; neuromuscular junction. Molecular Function: G-protein coupled receptor activity; protein binding; G-protein beta-subunit binding; G-protein alpha-subunit binding; receptor binding; thrombin receptor activity. Biological Process: elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of blood coagulation; activation of MAPKK activity; negative regulation of glomerular filtration; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; positive regulation of caspase activity; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; negative regulation of cell proliferation; elevation of cytosolic calcium ion concentration; connective tissue replacement during inflammatory response; positive regulation of MAPKKK cascade; platelet dense granule organization and biogenesis; regulation of interleukin-1 beta production; positive regulation of cell proliferation; protein kinase C activation; response to wounding; negative regulation of neuron apoptosis; positive regulation of smooth muscle contraction; inflammatory response; establishment of synaptic specificity at neuromuscular junction; STAT protein nuclear translocation; caspase activation; platelet activation; anatomical structure morphogenesis; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of Rho protein signal transduction; positive regulation of phosphoinositide 3-kinase cascade; G-protein coupled receptor protein signaling pathway; tyrosine phosphorylation of STAT protein; homeostasis of number of cells within a tissue; release of sequestered calcium ion into cytosol; regulation of blood coagulation; positive regulation of vasoconstriction; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of release of sequestered calcium ion into cytosol; regulation of sensory perception of pain; positive regulation of calcium ion transport; blood coagulation; positive regulation of cell migration

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

675

more info or order :

MyBioSource product webpage