catalog number :
MBS740940
products type :
ELISA Kit
products full name :
Porcine Diamine Oxidase ELISA Kit
products short name :
[Diamine Oxidase]
other names :
[amiloride-sensitive amine oxidase; Amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase [copper-containing]; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein 1; amine oxidase copper domain-containing protein 1; amiloride binding protein 1 (amine oxidase (copper-containing)); amine oxidase, copper containing 1; Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase; KAO]
products gene name :
[DAO]
other gene names :
[AOC1; AOC1; ABP; DAO; KAO; ABP1; DAO1; ABP1; DAO1; DAO; Diamine oxidase; KAO]
uniprot entry name :
AOC1_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of DAO. No significant cross-reactivity or interference between DAO and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between DAO and all the analogues, therefore, cross reaction may still exist in some cases.
storage stability :
Store all reagents at 2-8 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. Sensitivity: 0.1 ng/mL
products description :
Intended Uses: This DAO ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Porcine DAO. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
ncbi acc num :
NP_001259001.1
ncbi gb acc num :
NM_001272072.1
ncbi mol weight :
87,239 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Histidine Metabolism Pathway (82958); Histidine Metabolism Pathway (324); Tryptophan Metabolism Pathway (82964); Tryptophan Metabolism Pathway (198850); Tryptophan Metabolism Pathway (332); Histamine Degradation Pathway (545334); Histamine Degradation Pathway (139087)
ncbi summary :
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
uniprot summary :
ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - histidine; Secreted; Secreted, signal peptide; EC 1.4.3.22; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - tryptophan; Oxidoreductase. Chromosomal Location of Human Ortholog: 7q36.1. Cellular Component: extracellular space; tight junction; plasma membrane; peroxisome. Molecular Function: heparin binding; amine oxidase activity; protein homodimerization activity; copper ion binding; zinc ion binding; protein complex binding; drug binding; receptor activity; calcium ion binding; cation channel activity; sodium channel activity; quinone binding. Biological Process: response to antibiotic; response to drug; amine metabolic process
size4 :
10x96-Strip-Wells