catalog number :
MBS736322
products type :
ELISA Kit
products full name :
Sheep 17-Alpha Hydroxylase ELISA Kit
products short name :
17-Alpha Hydroxylase
other names :
steroid 17-alpha-hydroxylase/17,20 lyase; Steroid 17-alpha-hydroxylase/17,20 lyase; steroid 17-alpha-hydroxylase/17,20 lyase; CYPXVII; cytochrome P450c17; cytochrome P450-C17; cytochrome P450 17A1; cytochrome p450 XVIIA1; steroid 17-alpha-monooxygenase; 17-alpha-hydroxyprogesterone aldolase; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; cytochrome P450, family 17, subfamily A, polypeptide 1; 17-alpha-hydroxyprogesterone aldolase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; Steroid 17-alpha-monooxygenase
products gene name :
S17AH
other gene names :
CYP17A1; CYP17A1; CPT7; CYP17; S17AH; P450C17; CYP17; S17AH; Cytochrome P450c17
uniprot entry name :
CP17A_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
ncbi acc num :
NP_000093.1
ncbi gb acc num :
NM_000102.3
ncbi mol weight :
57,371 Da
ncbi pathways :
Androgen Biosynthesis Pathway 106154!!Biological Oxidations Pathway 105698!!C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway 413383!!C19/C18-Steroid Hormone Biosynthesis, Pregnenolone = Androstenedione = Estrone Pathway 468268!!C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway 413395!!C21-Steroid Hormone Biosynthesis, Progesterone = Cortisol/cortisone Pathway 468370!!Cytochrome P450 - Arranged By Substrate Type Pathway 105700!!Endogenous Sterols Pathway 105701!!Glucocorticoid Mineralcorticoid Metabolism Pathway 198902!!Glucocorticoid Biosynthesis Pathway 106152
ncbi summary :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]