catalog number :
MBS736206
products type :
ELISA Kit
products full name :
Canine C terminal Telopeptides of type l collagen ELISA Kit
products short name :
C terminal Telopeptides of type l collagen
other names :
C-C chemokine receptor type 6; C-C chemokine receptor type 6; C-C chemokine receptor type 6; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; chemokine (C-C motif) receptor 6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen: CD196
products gene name :
CTx1
other gene names :
CCR6; CCR6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; CKRL3; CMKBR6; GPR29; STRL22; C-C CKR-6; CC-CKR-6; CCR-6; CKR-L3; GPRCY4
uniprot entry name :
CCR6_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Cardiovascular
ncbi acc num :
NP_113597.2
ncbi gb acc num :
NM_031409.3
ncbi mol weight :
42,494 Da
ncbi pathways :
Beta Defensins Pathway (530759); Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Defensins Pathway (530757); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548)
ncbi summary :
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
CCR6: Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; innate immune response; cellular defense response; dendritic cell chemotaxis; immune response; signal transduction; cell motility; chemotaxis; humoral immune response