catalog number :
MBS731853
products type :
ELISA Kit
products full name :
Human B Cell Activating Factor Receptor ELISA Kit
products short name :
B Cell Activating Factor Receptor
other names :
BAFF receptor; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily member 13C; BAFF receptor; BLyS receptor 3; B cell-activating factor receptor; B-cell-activating factor receptor; tumor necrosis factor receptor superfamily, member 13C; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD_antigen: CD268
products gene name :
BAFFR
other gene names :
TNFRSF13C; TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin; BAFFR; BR3; BAFF-R
uniprot entry name :
TR13C_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info2 :
ELISA Method: Sandwich. Highest Standards: 5000pg/mL. Concentration of Standards: Concentration of Standards: 0,250,500,1000,2500,5000pg/mL
products categories :
Cell Biology
ncbi acc num :
AAI12031.1
ncbi mol weight :
18,935 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Intestinal Immune Network For IgA Production Pathway 128760!!Intestinal Immune Network For IgA Production Pathway 128670!!NF-kappa B Signaling Pathway 634527!!Primary Immunodeficiency Pathway 83125!!Primary Immunodeficiency Pathway 537
ncbi summary :
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]