ELISA/assay

Rat C terminal Telopeptides of type l collagen ELISA Kit

MBS731770

48-Strip-Wells-(Comp

470 USD

ELISA Kit

Rat C terminal Telopeptides of type l collagen ELISA Kit

C terminal Telopeptides of type l collagen

C-C chemokine receptor type 6; C-C chemokine receptor type 6; C-C chemokine receptor type 6; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; chemokine (C-C motif) receptor 6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen: CD196

CTx1

CCR6; CCR6; BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6; CKRL3; CMKBR6; GPR29; STRL22; C-C CKR-6; CC-CKR-6; CCR-6; CKR-L3; GPRCY4

CCR6_HUMAN

Rat

This assay has high sensitivity and excellent specificity for detection of CTx-1. No significant cross-reactivity or interference between CTx-1 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between CTx-1 and all the analogues, therefore, cross reaction may still exist in some cases.

Store all reagents at 2-8 degree C.

Assay Type: Competitive or Sandwich. Samples: Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. Sensitivity: 1.0 pg/mL.

Cardiovascular

Intended Uses: This CTx-1 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rat CTx-1. This ELISA kit for research use only, not for therapeutic or diagnostic applications!. Principle of the Assay CTx-1 ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for CTx-1. Standards or samples are then added to the microtiter plate wells and CTx-1 if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of CTx-1 present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody, specific for CTx-1 are added to each well to "sandwich" the CTx-1 immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain CTx-1 and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The CTx-1 concentration in each sample is interpolated from this standard curve.

37188165

NP_113597.2

NM_031409.3

42,494 Da

Beta Defensins Pathway (530759); Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Defensins Pathway (530757); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548)

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

CCR6: Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; receptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; innate immune response; dendritic cell chemotaxis; cellular defense response; immune response; cell motility; signal transduction; chemotaxis; humoral immune response

48-Strip-Wells-(Competitive)

470 USD

48-Strip-Wells-(Sandwich)

470

96-Strip-Wells-(Competitive)

675

96-Strip-Wells-(Sandwich)

675