ELISA/assay

Human A Disintegrin And Metalloprotease 8 ELISA Kit

MBS731186

48-Strip-Wells-(Comp

470 USD

ELISA Kit

Human A Disintegrin And Metalloprotease 8 ELISA Kit

A Disintegrin And Metalloprotease 8

ADAM8 protein; Disintegrin and metalloproteinase domain-containing protein 8; disintegrin and metalloproteinase domain-containing protein 8; cell surface antigen MS2; human leukocyte differentiation antigen; a disintegrin and metalloproteinase domain 8; ADAM metallopeptidase domain 8; Cell surface antigen MS2; CD_antigen: CD156a

ADAM8

ADAM8; ADAM8; MS2; CD156; CD156a; MS2; ADAM 8

ADAM8_HUMAN

Human

Store all reagents at 2-8 degree C.

Assay Type: Competitive or Sandwich

Highest Standards: 1000 pg/mL. Concentration of Standards: Concentration of Standards: 0,50,100,250,500,1000 pg/mL

Cardiovascular

109731932

AAI15405.1

80,262 Da

Degradation Of The Extracellular Matrix Pathway (576263); Extracellular Matrix Organization Pathway (576262)

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]

ADAM8: Possible involvement in extravasation of leukocytes. Protein type: Membrane protein, integral; Protease; Motility/polarity/chemotaxis; EC 3.4.24.-. Chromosomal Location of Human Ortholog: 10q26.3. Cellular Component: specific granule; cell surface; integral to plasma membrane; cytoplasm; plasma membrane; podosome; dense core granule membrane. Molecular Function: protein binding; protein self-association; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; cell adhesion molecule binding; calcium ion binding. Biological Process: extracellular matrix organization and biogenesis; positive regulation of cell adhesion; cell morphogenesis; proteolysis; positive regulation of membrane protein ectodomain proteolysis; leukocyte migration during inflammatory response; activation of NF-kappaB transcription factor; positive regulation of T cell differentiation in the thymus; extracellular matrix disassembly; positive regulation of protein kinase B signaling cascade; cell-cell adhesion; regulation of cell-cell adhesion; positive regulation of protein secretion; positive regulation of acute inflammatory response; positive regulation of bone resorption; angiogenesis; negative regulation of neuron apoptosis; inflammatory response; lymphocyte chemotaxis

48-Strip-Wells-(Competitive)

470 USD

48-Strip-Wells-(Sandwich)

470

96-Strip-Wells-(Competitive)

675

96-Strip-Wells-(Sandwich)

675