catalog number :
MBS731024
products type :
ELISA Kit
products full name :
Human B Cell CLL/Lymphoma 10 ELISA Kit
products short name :
B Cell CLL/Lymphoma 10
other names :
B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; hCLAP; cCARMEN; cellular-E10; cellular homolog of vCARMEN; CARD-containing proapoptotic protein; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; caspase-recruiting domain-containing protein; CARD-containing molecule enhancing NF-kappa-B; mammalian CARD-containing adapter molecule E10; CED-3/ICH-1 prodomain homologous E10-like regulator; B-cell CLL/lymphoma 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10
products gene name :
Bcl10
other gene names :
BCL10; BCL10; CLAP; mE10; CIPER; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
uniprot entry name :
BCL10_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
products categories :
Cell Biology
ncbi acc num :
NP_003912.1
ncbi gb acc num :
NM_003921.4
ncbi mol weight :
26,252 Da
ncbi pathways :
Activation Of NF-kappaB In B Cells Pathway 576251!!Adaptive Immune System Pathway 366160!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!BCR Signaling Pathway 138058!!Canonical NF-kappaB Pathway 138030!!Downstream TCR Signaling Pathway 106418!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!FCERI Mediated NF-kB Activation Pathway 833828
ncbi summary :
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]