catalog number :
MBS729482
products type :
ELISA Kit
products full name :
Rat Interleukin 31 ELISA Kit
products short name :
Interleukin 31
other names :
interleukin-31; Interleukin-31; interleukin-31; interleukin 31
products gene name :
IL-31
other gene names :
IL31; IL31; IL-31; IL-31
uniprot entry name :
IL31_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Sensitivity: 1.0 pg/mL.
other info2 :
Intended Uses: This IL-31 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rat IL-31. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
products categories :
Immunology
ncbi acc num :
NP_001014358.1
ncbi gb acc num :
NM_001014336.1
ncbi mol weight :
18,205 Da
ncbi summary :
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
uniprot summary :
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. Protein type: Secreted, signal peptide; Cytokine; Secreted. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: extracellular space. Molecular Function: cytokine activity. Biological Process: immune system process