catalog number :
MBS729463
products type :
ELISA Kit
products full name :
Human Hepatic lipase ELISA Kit
products short name :
Hepatic lipase
other names :
hepatic triacylglycerol lipase; Hepatic triacylglycerol lipase; hepatic triacylglycerol lipase; hepatic lipase; lipase member C; lipase, hepatic; Lipase member C
other gene names :
LIPC; LIPC; HL; HTGL; LIPH; HDLCQ12; HTGL; HL; Hepatic lipase
uniprot entry name :
LIPC_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive or Sandwich
other info2 :
Highest Standards: 100ng/mL. Concentration of Standards: Concentration of Standards: 0,5,10,25,50,100ng/mL
ncbi acc num :
NP_000227.2
ncbi gb acc num :
NM_000236.2
ncbi mol weight :
55,914 Da
ncbi pathways :
Acylglycerol Degradation Pathway (413388); Acylglycerol Degradation Pathway (468272); Chylomicron-mediated Lipid Transport Pathway (106157); Fatty Acid Beta Oxidation Pathway (198865); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolic Pathways (132956); Metabolism Pathway (477135)
ncbi summary :
LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008]
uniprot summary :
LIPC: Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin. Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency). A disorder characterized by elevated levels of beta-migrating very low density lipoproteins, and abnormally triglyceride-rich low and high density lipoproteins. Belongs to the AB hydrolase superfamily. Lipase family. Protein type: Secreted, signal peptide; Lipid Metabolism - glycerolipid; Secreted; EC 3.1.1.3; Phospholipase. Chromosomal Location of Human Ortholog: 15q21-q23. Cellular Component: extracellular space. Molecular Function: heparin binding; triacylglycerol lipase activity; low-density lipoprotein binding; apolipoprotein binding; phospholipase activity. Biological Process: cholesterol metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol catabolic process; fatty acid biosynthetic process. Disease: High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 12; Hepatic Lipase Deficiency; Diabetes Mellitus, Noninsulin-dependent
size1 :
48-Strip-Wells-(Competitive)
size2 :
48-Strip-Wells-(Sandwich)
size3 :
96-Strip-Wells-(Competitive)
size4 :
96-Strip-Wells-(Sandwich)