product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Nuclear RNA Export Factor 1 ELISA Kit
catalog :
MBS729220
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
product information
catalog number :
MBS729220
products type :
ELISA Kit
products full name :
Rat Nuclear RNA Export Factor 1 ELISA Kit
products short name :
Nuclear RNA Export Factor 1
other names :
nuclear RNA export factor 1 isoform 2; Nuclear RNA export factor 1; nuclear RNA export factor 1; mRNA export factor TAP; tip-associated protein; tip associating protein; tip-associating protein; nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP
products gene name :
NXF1
other gene names :
NXF1; NXF1; TAP; MEX67; TAP
uniprot entry name :
NXF1_HUMAN
reactivity :
Rat
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 1000pg/mL. Concentration of Standards: Concentration of Standards: 0,50,100,250,500,1000pg/mL
ncbi gi num :
125625324
ncbi acc num :
NP_001074960.1
ncbi gb acc num :
NM_001081491.1
ncbi mol weight :
40,476 Da
ncbi pathways :
Gene Expression Pathway (105937); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Influenza A Pathway (217173); Influenza A Pathway (217150); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); RNA Transport Pathway (177876); RNA Transport Pathway (175229); Ribosome Biogenesis In Eukaryotes Pathway (199378); Ribosome Biogenesis In Eukaryotes Pathway (199266)
ncbi summary :
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
uniprot summary :
NXF1: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5. Belongs to the NXF family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: RNA-binding. Chromosomal Location of Human Ortholog: 11q12-q13. Cellular Component: nucleoplasm; nuclear pore; nuclear speck; cytosol; nuclear inclusion body. Molecular Function: mRNA binding; protein binding; nucleotide binding; nucleocytoplasmic transporter activity. Biological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus; viral reproduction; gene expression
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
675
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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