catalog number :
MBS727516
products type :
ELISA Kit
products full name :
Mouse Angiotensinogen ELISA Kit
products short name :
Angiotensinogen
other names :
angiotensinogen; Angiotensinogen; angiotensinogen; serpin A8; angiotensin I; angiotensin II; pre-angiotensinogen; alpha-1 antiproteinase, antitrypsin; serine (or cysteine) proteinase inhibitor; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Serpin A8Cleaved into the following 8 chains:Angiotensin-1Alternative name(s):Angiotensin 1-10; Angiotensin I; Ang I
other gene names :
AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV
uniprot entry name :
ANGT_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info2 :
ELISA Method: Competitive. Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1.0,2.5,5.0,10,25ng/mL
products categories :
Cardiovascular
ncbi acc num :
AAA51679.1
ncbi mol weight :
53,154 Da
ncbi pathways :
ACE Inhibitor Pathway 198763!!Adipogenesis Pathway 198832!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!G Alpha (i) Signalling Events Pathway 119550!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Metabolism Pathway 477135
ncbi summary :
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]