catalog number :
MBS727102
products type :
ELISA Kit
products full name :
Rat Calumenin ELISA Kit
products short name :
Calumenin
other names :
calumenin; Calumenin; calumenin; IEF SSP 9302; crocalbin-like protein; multiple EF-hand protein; calumenin; Crocalbin; IEF SSP 9302
products gene name :
CALU
other gene names :
CALU; CALU
uniprot entry name :
CALU_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1.0,2.5,5.0,10,25ng/mL
products categories :
Cell Biology
ncbi acc num :
AAB97725.1
ncbi mol weight :
19,455 Da
ncbi pathways :
Hemostasis Pathway (106028); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)
ncbi summary :
The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
uniprot summary :
CALU: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. Belongs to the CREC family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Calcium-binding. Chromosomal Location of Human Ortholog: 7q32.1. Cellular Component: Golgi apparatus; sarcoplasmic reticulum lumen; membrane; endoplasmic reticulum; extracellular region; melanosome. Molecular Function: protein binding; calcium ion binding. Biological Process: platelet activation; platelet degranulation; blood coagulation