ELISA/assay

Human Soluble Interleukin 2a receptor ELISA Kit

MBS726822

48-Strip-Wells-(Comp

470 USD

ELISA Kit

Human Soluble Interleukin 2a receptor ELISA Kit

Soluble Interleukin 2a receptor

interleukin 2 receptor, alpha, isoform CRA_a, partial; Interleukin-2 receptor subunit alpha; interleukin-2 receptor subunit alpha; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; interleukin 2 receptor, alpha; TAC antigen; p55; CD_antigen: CD25

IL 2sRa

IL2RA; IL2RA; p55; CD25; IL2R; TCGFR; IDDM10; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA

IL2RA_HUMAN

Human

Store all reagents at 2-8 degree C.

Assay Type: Competitive or Sandwich

Highest Standards: 2500pg/mL. Concentration of Standards: Concentration of Standards: 0,100,250,500,1000,2500pg/mL

Immunology

119606818

EAW86412.1

30,819 Da

Arf6 Trafficking Events Pathway (137954); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Calcium Signaling In The CD4+ TCR Pathway (137941); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Downstream Signaling In Naive CD8+ T Cells Pathway (138018); Endocytosis Pathway (102279); Endocytosis Pathway (102181); HTLV-I Infection Pathway (373901)

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 10p15-p14. Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane. Molecular Function: interleukin-2 receptor activity; drug binding; interleukin-2 binding. Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; apoptosis; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; cell proliferation; inflammatory response to antigenic stimulus; negative regulation of T cell proliferation; cell surface receptor linked signal transduction; positive regulation of T cell differentiation; negative regulation of inflammatory response; immune response; inflammatory response; activated T cell apoptosis. Disease: Interleukin 2 Receptor, Alpha, Deficiency Of; Diabetes Mellitus, Insulin-dependent, 10

48-Strip-Wells-(Competitive)

470 USD

48-Strip-Wells-(Sandwich)

470

96-Strip-Wells-(Competitive)

675

96-Strip-Wells-(Sandwich)

675