product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Extracellular Matrix Protein 1 ELISA Kit
catalog :
MBS726189
quantity :
48-Strip-Wells-(Comp
price :
470 USD
more info or order :
product information
catalog number :
MBS726189
products type :
ELISA Kit
products full name :
Human Extracellular Matrix Protein 1 ELISA Kit
products short name :
Extracellular Matrix Protein 1
other names :
extracellular matrix protein 1; Extracellular matrix protein 1; Secretory component p85
products gene name :
ECM1
other gene names :
ECM1
uniprot entry name :
ECM1_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive or Sandwich
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1,2.5,5.0,10,25ng/mL
products categories :
Neurobiology
ncbi gi num :
2654433
ncbi acc num :
AAB88081.1
ncbi mol weight :
63,563 Da
uniprot summary :
ECM1: Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. Defects in ECM1 are the cause of lipoid proteinosis (LiP); also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space. Molecular Function: protein C-terminus binding; signal transducer activity; protein binding; enzyme binding; protease binding; interleukin-2 receptor binding; laminin binding. Biological Process: regulation of transcription from RNA polymerase II promoter; negative regulation of bone mineralization; positive regulation of angiogenesis; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; biomineral formation; negative regulation of peptidase activity; negative regulation of cytokine and chemokine mediated signaling pathway; positive regulation of endothelial cell proliferation; angiogenesis; regulation of T-helper 2 type immune response; signal transduction; inflammatory response. Disease: Lipoid Proteinosis Of Urbach And Wiethe
size1 :
48-Strip-Wells-(Competitive)
price1 :
470 USD
size2 :
48-Strip-Wells-(Sandwich)
price2 :
470
size3 :
96-Strip-Wells-(Competitive)
price3 :
675
size4 :
96-Strip-Wells-(Sandwich)
price4 :
675
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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