catalog number :
MBS725424
products type :
ELISA Kit
products full name :
Mouse CytoKeratin 18 ELISA Kit
products short name :
CytoKeratin 18
other names :
cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
products gene name :
CK 18
other gene names :
KRT18; KRT18; K18; CYK18; CYK18; PIG46; CK-18; K18
uniprot entry name :
K1C18_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info1 :
Assay Type: Competitive
other info2 :
Highest Standards: 25ng/mL. Concentration of Standards: Concentration of Standards: 0,1.0,2.5,5.0,10,25ng/mL
products categories :
Cell Biology
ncbi acc num :
CAA31375.1
ncbi mol weight :
48,058 Da
ncbi pathways :
Caspase Cascade In Apoptosis Pathway (137974); EGFR1 Signaling Pathway (198782); Pathogenic Escherichia Coli Infection Pathway (83103); Pathogenic Escherichia Coli Infection Pathway (672459); Pathogenic Escherichia Coli Infection Pathway (516)
ncbi summary :
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
K18: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Defects are a cause of cryptogenic cirrhosis. Protein type: Nucleolus; Cytoskeletal. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: perinuclear region of cytoplasm; cytoplasm; keratin filament; nucleolus; intermediate filament; microtubule organizing center. Molecular Function: protein binding; structural molecule activity. Biological Process: anatomical structure morphogenesis; viral reproduction; tumor necrosis factor-mediated signaling pathway; intermediate filament cytoskeleton organization and biogenesis; cell cycle; negative regulation of apoptosis; Golgi to plasma membrane CFTR protein transport. Disease: Cirrhosis, Familial