catalog number :
MBS725387
products type :
ELISA Kit
products full name :
Mouse Cytochrome P450 2E1 ELISA Kit
products short name :
Cytochrome P450 2E1
other names :
cytochrome P450 2E1; Cytochrome P450 2E1; cytochrome P450 2E1; CYPIIE1; cytochrome P450-J; microsomal monooxygenase; xenobiotic monooxygenase; 4-nitrophenol 2-hydroxylase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; cytochrome P450, family 2, subfamily E, polypeptide 1; 4-nitrophenol 2-hydroxylase (EC:1.14.13.n7); CYPIIE1; Cytochrome P450-JCleaved into the following chain:Cytochrome P450 2E1, N-terminally processed
products gene name :
CYP2E1
other gene names :
CYP2E1; CYP2E1; CPE1; CYP2E; P450-J; P450C2E; CYP2E
uniprot entry name :
CP2E1_HUMAN
storage stability :
Store all reagents at 2-8 degree C.
other info2 :
ELISA Method: Competitive. Highest Standards: 10ng/mL. Concentration of Standards: Concentration of Standards: 0,0.5,1.0,2.5,5.0,10ng/mL
ncbi acc num :
NP_000764.1
ncbi gb acc num :
NM_000773.3
ncbi mol weight :
56,849 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 366!!Biological Oxidations Pathway 105698!!CYP2E1 Reactions Pathway 105705!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Cytochrome P450 - Arranged By Substrate Type Pathway 105700!!Drug Metabolism - Cytochrome P450 Pathway 83032!!Drug Metabolism - Cytochrome P450 Pathway 427!!Fatty Acid Omega Oxidation Pathway 198915
ncbi summary :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]